Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride

Pemmer, B.; Hofstaetter, J.G.; Meirer, F.; Smolek, S.; Wobrauschek, P.; Simon, R.; Fuchs, R.K.; Allen, M.R.; Condon, K.W.; Reinwald, S.; Phipps, R.J.; Burr, D.B.; Paschalis, E.P.; Klaushofer, K.; Streli, C.; Roschger, P.

doi:10.1107/S090904951103038X

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Figure 1
Examples of qBEI images and the corresponding SR µ-XRF elemental maps of calcium (Ca) and strontium (Sr) based on Ca Kα and Sr Kα fluorescence lines, respectively, from bone samples of animals untreated and treated by SrR or SrCl₂: (a) untreated, (b) low Sr dose at normal Ca diet, (c) low Sr dose at deficient Ca diet, (d) high Sr dose at normal Ca, and (e) high Sr dose at deficient Ca. The pixel size of the SR µ-XRF elemental maps is 10 µm × 10 µm with a depth resolution of 12 µm at Sr Kα (14.2 keV). The color-coded X-ray intensities (counts s⁻¹) are scaled from minimum to maximum. qBEI shows young bone packets (less mineralized) as darker, and older bone packets as well as residual cartilage (higher mineralized) as brighter gray levels.

JOURNAL OF
SYNCHROTRON
RADIATION

ISSN: 1600-5775

Volume 18| Part 6| September 2011| Pages 835-841

doi:10.1107/S090904951103038X

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