Preclinical radiotherapy at the Australian Synchrotron's Imaging and Medical Beamline: instrumentation, dosimetry and a small-animal feasibility study

Livingstone, J.; Adam, J.F.; Crosbie, J.C.; Hall, C.J.; Lye, J.E.; McKinlay, J.; Pelliccia, D.; Pouzoulet, F.; Prezado, Y.; Stevenson, A.W.; Häusermann, D.

doi:10.1107/S1600577517006233

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Figure 8
Crossfired irradiation geometries as seen in the axial plane for MRT (left) and MBRT (right). The target outline is represented by the dotted line and the crossfired area is represented by the thick solid line. The numbers represent a dose (in Gy) for each region, based on a simplified case with a hypothetical valley dose of 1 Gy for each modality, so that the values in the peaks are equivalent to the corresponding PVDRs for the treatment depth and field size. The integrated doses for these simplified cases are 12.75 Gy and 14 Gy for MRT and MBRT, respectively. The beam attenuation has been neglected over the target dimensions for simplification purposes. In the feasibility study, an integrated dose of 65 Gy was prescribed to 10 mm depth in water using a 10 mm × 10 mm field size. This corresponds to real valley doses of 5 Gy and 4.6 Gy for MRT and MBRT, respectively.

JOURNAL OF
SYNCHROTRON
RADIATION

ISSN: 1600-5775

Volume 24| Part 4| July 2017| Pages 854-865

https://doi.org/10.1107/S1600577517006233

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