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Figure 5
(a) Group mean of the MTT of the vessels in normal tissue (n = 4), MDAMB231 (n = 9) and MDAMB231NOTCH4+ (n = 8). The MTT was longer in MDAMB231 than in normal tissue. In mice bearing MDAMB231NOTCH4+, the MTT significantly decreased (MDAMB231: 5.0 ± 1.4 s; normal: 3.6 ± 1.0 s; MDAMB231NOTCH4+: 3.6 ± 1.1 s). (b) Representative plots of MTT in each group. MTT shows a similar duration in each branch in all groups. (c) Left: no correlation was observed between the MTT of the vessels and tumor volume in MDAMB231 (n = 9). Right: correlation between the MTT of the vessels and tumor volume following three weeks of eribulin treatment (MDAMB231_eribulin) (n = 3). With the enlargement of volume, MTT significantly increased. ** p < 0.05. The error bars show SD of the mean. r: Pearson's correlation coefficient.

Journal logoJOURNAL OF
SYNCHROTRON
RADIATION
ISSN: 1600-5775
Volume 24| Part 5| September 2017| Pages 1039-1047
https://doi.org/10.1107/S1600577517008372
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