Figure 2
Correlation between PB-SRµCT and histological images in a rat model of PTS. (A–D) Sagittal and axial views of PB-SRµCT images showing a large cavity (yellow arrow). (E–H) The corresponding H&E staining images demonstrate the cord cavity. (I) The intensity profile of the corresponding line marked in (B–D) (spinal cord tissue: 1 and 5; boundary of the cavity: 2 and 5; cavity: 3). (J) Quantification of the lesion size and spared tissue within the injury site and 1200 µm distance rostral and caudal to the epicenter after cavity induction. (K) Comparison between the cavity area and mean diameter by PB-SRµCT and histological studies (r = 0.9544 and 0.9119, respectively). Scale bar = 200 µm. |