Figure 4
Cytotoxic effects of X-rays without and with ICp6-Cu pre-treatment in oral cancer cells determined by MTT assay. Changes in percent cell viability in NT8e (a) and 4451 (b) cells as a function of X-ray dose; the cells were pre-treated with 10, 20 and 30 µM ICp6-Cu for 3 h. Percent cell viability was calculated with respect to a control sample (without ICp6-Cu treatment). (c) Percent loss of cell viability in NT8e and 4451 for X-rays alone and X-rays plus ICp6-Cu at 7 Gy X-ray dose. *(p < 0.05), **(p < 0.01), ***(p < 0.005) indicate significant difference. Each data point is mean ± standard deviation of three independent experiments. |