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Figure 1
Effect of baseline variation on chlorine quantitation. (a) Representative XRF signals from individual cell (black) and blank (red) pixels with the calculated blank from this image (cyan) and multiple images (blue). Individual per-pixel baselines for all of the pixels are shown in gray and pink; baselines for the two pixels where the XRF is shown are the black and red dashed lines. The black arrow indicates the position of the chlorine peak. (b) Integrated baseline amplitude at the chlorine Kα peak ± 50 eV. (c) Quantitation for chlorine using per-pixel baseline correction, showing an apparent decrease in chlorine signal in the cell relative to the background (after removing the background, this would give an apparent negative chlorine concentration). (d) Quantitation for chlorine using M-BLANK. Black and red squares in (b)–(d) identify the pixels used in (a). The scale bar represents 2 µm.

Journal logoJOURNAL OF
SYNCHROTRON
RADIATION
ISSN: 1600-5775
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