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Figure 8
Fast tomography of the chest region of an ex vivo mouse, displayed with (a) edge-enhancement and (b) the result obtained using phase retrieval with the Paganin algorithm with a δ-to-β ratio optimized for lung soft tissue [thus bony structures are blurred (e.g. Beltran et al., 2010BB11)]. (c) Combined rendering of the data-set. Only the lungs are rendered using the phase-retrieved reconstruction, the other parts are from the edge-enhanced reconstruction. The high-refractive-index glass beads in the respiratory system are shown in blue. (d) Segmentation and rendering of the upper part of the left lung lobe of the phase-retrieved reconstruction. Note that 2 × 2 binning was used, resulting in an effective pixel size of 13 µm of the Hamamatsu detector. The sample-to-detector distance was 0.5 m. 1500 projections were acquired over 360° in 5 min while rotating continuously at a speed of 1.2° s−1 with 0.2 s × exposure time per projection. The input value for phase retrieval was δ/β = 1891, an approximation for lung tissue described by H10C0.83O5 (Mohammadi et al., 2014BB84).

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