Figure 9
Fast tomography of the chest region of an in vivo mouse, displayed with (a) edge-enhancement and (b) the respective result from the Paganin reconstruction with a δ-to-β ratio optimized for lung soft tissue. (c) Combined rendering of the data set. One side of the lung is segmented and rendered using the phase-retrieved reconstruction; the bones and beads are from the edge-enhanced reconstruction. The high-refractive-index glass beads in the respiratory system are shown in blue. (d) Zoomed-in region, showing that even in an in vivo mouse small airways remain visible, albeit with some motion blur. 2 × 2 binning is used for reconstruction, resulting in an effective pixel size of 13 µm of the Hamamatsu detector. 1000 frames were acquired over 360° at an acquisition time of 0.2 s. Since the images had to be taken during a short breath hold, the rotation speed was reduced to 0.4° s−1 resulting in a total time of 15 min. |