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Figure 6
(a) ROI centered around an islet of Langerhans, identified within reconstructed xy-slices of the unstained pancreatic cancer tissue punch biopsy (Sample A), from parallel-beam scan. The dashed red line indicates the islet of Langerhans. (b) ROI within reconstructed xy-slice of Sample A, from cone-beam scan. Resolution is enhanced and finer structures are resolved. Cell nuclei are marked by white arrows. (c) ROI within a reconstructed xy-slice of the PTA-stained PDAC tissue of biopsy Sample B, from parallel-beam scan. Magnified area: single cells located inside the islet of Langerhans are resolved. (d) ROI within a reconstructed xy-slices of Sample B, from cone-beam scan. Single-cell nuclei are visible. Magnified area: nuclei of cells which form the islet of Langerhans are resolved, marked by the white arrows. Scale bars: (a, b) 25 µm, (c, d) 75 µm and magnified areas 10 µm.

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