Figure 3
Synchrotron WFUV allows detection of CaOx macrocrystallites in kidney biopsies. (A, B) Scanning electron microscope observations of typical CaOx macrocrystallites in the tubule lumens. Fluorescence is bright in the 412–438 nm channel (C) and shallow in the 327–353 nm channel (D) which results in a yellow subtract signal (E) evocative of CaOx composition. (F) Macrocrystal presence is significantly more frequent in PHO and SHO patients than in control biopsies, while it is not frequent in KLTPHO patients. ** p < 0.01; * p < 0.05; ns: not significant. |