Figure 3
Localization of silica core-shell Au NS in PC 12 following exposure to SS THz radiation. (a) STEM micrographs illustrating SS THz irradiated PC 12 cells. NS are seen internalized in vacuoles (yellow arrows) inside the cytoplasm. (b) EDS spectra representative of the line data 1 in the electron microscopy image (a) confirming the presence of elemental Au (black arrows), thus confirming the presence of AuSi NS localized inside vacuoles in the cellular cytoplasm. (c) Quantification of the localization of AuSi NS. The majority of the NS are present in the cytoplasm and are sequestered in vacuoles. (d) STEM micrograph of the unexposed PC 12 cell sample and (e) representative EDS spectra. No peaks were detected for Au, line data 11, confirming the absence of Au inside the vacuoles that were observed inside the control cells. |