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Figure 5
Visual comparison of a PCCT scan of an FFPE rat lung tissue block before and after suppression of air artifacts. (a) A 3D rendering of a PCCT scan of FFPE rat lung tissue, with visible air artifacts (left), and the same scan after suppression of these artifacts using a trained pix2pix-cGAN generator model (right). To enhance visualization, a threshold above the paraffin intensity is applied in the 3D rendering. (b) A 2D slice from the same scan before (left) and after (right) suppression of air artifacts, corresponding to the dataset shown in (a). (c) Detailed views [marked in yellow in (b)] of specific regions – on the left, the original scan, and on the right, the scan after air artifact suppression. In the first example, air artifacts within the lung parenchyma are replaced with plausible lung tissue structures. In the second, air artifacts in a large vessel are reduced mainly in edge intensity, while, in the third, the artifact in a smaller vessel is replaced with dim, but visibly incorrect, lung tissue. The 3D and 2D visualizations demonstrate that suppression of air artifacts significantly improves the rendering and structural analysis of lung tissue, particularly in the parenchyma regions. |