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Figure 3
Shape and volume of lacunae from images denoised with N2I. (a) Lacunar volume was assessed for each of the networks, revealing that full-dose, half-dose and one-third dose experiments possessed similar lacunae volume distributions compared with the one-fourth and one-sixth dose simulated data. (b) Lacunae aspect ratio, the ratio of the minimum to the maximum eigenvectors of each lacunae, was compared for each of the simulated doses, revealing that lacunae tended to become more circle- or sphere-like as dose decreased compared with the more rod-like shape in the full-dose lacunae. (c)–(g) Representative 3D SRµCT images show the similarity between the full dose and one-third dose lacunae segmentations, whereas lacunae in the one-sixth dose segmentation may be larger and fewer. |