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Figure 6
Quantification of microstructural features for all samples used in full-dose and one-third dose N2I training. (a) Lacunae volume distributions varied significantly from the full-dose to the one-third dose experiments. The one-third dose experiments measured lower-volume lacunae. (b) Lacunae aspect ratio increased in the one-third dose simulations compared with the full-dose simulations. (c) Mineralization significantly decreased in the one-third dose simulations compared with that of the full-dose experiments. (d)–(f) Lacunae-volume, aspect-ratio and mineralization mode values are significantly shifted in the one-third simulated-dose samples compared with the full-dose simulated data (p < 0.01 for all). Data are given as the mean ± standard deviation. All statistics were performed with a paired t-test in Python. |