Response of pheochromocytoma neuronal cells to varying intensity of continuous wave terahertz radiation

Linklater, D.P.; Perera, P.G.T.; Vilagosh, Z.; Perez-Gonzalez, A.; Le, P.H.; Sharma, T.; Leeming, M.G.; Williamson, N.A.; Appadoo, D.; Croft, R.; Ivanova, E.P.

doi:10.1107/S1600577525008227

Journal of Synchrotron Radiation Journal of
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Figure 3
THz radiation-induced changes to DNA. FC analysis of PC 12 cells labelled with DAPI before (a) and after (b) HI THz exposure. Cells were gated using FSC versus SSC. Then single cells were gated using FSC-H versus FSC-A. Live cells were gated and cell cycle analysis was performed on DAPI-positive (+) cells. (c) Nuclear morphometric analysis showing quantification of nuclear area and circularity of control PC 12 and PC 12 exposed to HI THz. (d) Representative CLSM micrographs of control PC 12 cell nuclei (DAPI; blue) and nuclei of cells exposed to HI THz. (d) Viability of control PC 12 cells and cells exposed to HI THz.

JOURNAL OF
SYNCHROTRON
RADIATION

ISSN: 1600-5775

Volume 32| Part 6| November 2025| Pages 1431-1444

https://doi.org/10.1107/S1600577525008227

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