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Figure 7
Monitoring Aβ40 aggregation by near-simultaneous fluorescence and XFMS. (a) In-line fluorescence collected in the presence of ThT in Aβ40 at various delays after the initiation of aggregation by solvent transfer (see Method S2). (b) The kinetic traces of residue level modification in the presence (red) and absence (black) of ThT were obtained by exposing the sample to X-rays in the standard XFMS experiment 100–500 µs after in-line fluorescence collection. The solid line represents fitted data using a modified Boltzmann sigmoidal equation (Table S5).

Journal logoJOURNAL OF
SYNCHROTRON
RADIATION
ISSN: 1600-5775
Volume 33| Part 4| July 2026|
https://doi.org/10.1107/S1600577526003711
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