Figure 2
A superposition of the molecular conformations of clindamycin molecules, showing the planar central carboxamide groups. The overlay was made by making a least-squares fit through the planar carboxamide atoms of (I). The labels and r.m.s deviations (Å) of the carboxamide atoms are as follows: clindamycin hydrochloride monohydrate ethanol solvate, (II), 0.025; 1YJN, (III), 0.050; lincomycin hydrochloride, (IV), 0.025; clindamycin 2-phosphate hydrate, (V), 0.091 (even though there are three molecules in the asymmetric unit and their overlay is almost exact, only one molecule is represented here). Disordered atoms C151/C161/C171 of (I) and C161/C171 of (II) and all H atoms have been omitted for clarity. |