Figure 1
5-Phosphoarabinonate bound to human phosphoglucose isomerase at 2.5 Å resolution. A stereo picture of the active-site region, showing the 2(|Fo| − |Fc|) electron density of the bound inhibitor, contoured in blue at 1σ. The active-site residues and inhibitor molecules are shown in ball-and-stick form. The inhibitor is coloured red. This figure was prepared using PyMOL (DeLano, 2002). |