December 2011 issue
Cover illustration: The two-dimensional organization of Zn2+-cross-linked human transthyretin L55P dimers as observed from the crystal packing (p. 1035). The Zn2+-binding sites are highlighted and also the other residues from crystal-contact interactions, namely His56, Ala37 and Asp39. Dimers lying on different sides of this bilayer-like assembly are coloured differently. In this arrangement, the -strands from symmetry-related monomers have the same orientation and all the -strands are almost perpendicular to the vertical direction in the paper plane, configuring a cross- structure.