Figure 3
Missing density: extended glycosylations. The specific conformation of the last three α-D-mannose moieties (A5–A7) of the extended branched glycosylation in PDB entry 3ib0 (Mir et al., 2009) is unsupported by electron density in the structure of bovine lactotransferrin, while the first two sugar moieties (A3–A4) are clearly present. The 1.4 Å resolution mFo − DFc map contoured at +3σ (green) was calculated after refining a model omitting the sugar moieties of the glycosylation site. |