Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling

Zhang, B.; Liu, C.; Qian, W.; Han, Y.; Li, X.; Deng, J.

doi:10.1107/S1399004714005227

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 1
The unique structure of IL-17RA SEFIR. (a) Stereoview of the IL-17RA SEFIR domain. The secondary structures are shown as rainbow-colored ribbons and are labeled. (b) Pairwise comparison with IL-17RB SEFIR. Depicted is a stereoview of the superimposed structures of the SEFIR domains from IL-17RA (green) and IL-17RB (red). The secondary structures with the greatest topological and conformational differences are labeled.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 70| Part 5| May 2014| Pages 1476-1483

https://doi.org/10.1107/S1399004714005227

Open

access

Follow Acta Cryst. D

Search IUCr Journals		doi		Advanced search
Author		volume	page