 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 2]](rf5027fig2mag.jpg)
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Figure 2
(a, b) Close-up of an inter-domain loop overlay of the crystal structures of (a) the C318A (gray; PDB entry 2hgw; Yennawar et al., 2006  ) and C318A/C315CSD (blue) mutants and (b) the oxidized wild type (orange/yellow; PDB entry 2hhf; Yennawar et al., 2006) and the C318A/C315CSD mutant (blue). The interdomain loop (residues 171–181, highlighted by the circle), which was missing in the C318A mutant owing to a lack of electron density, was interpreted in one of the monomers of the C318A/C315CSD mutant (a) and mimics the interdomain loop of oxidized wild-type hBCATm (b). (c, d) Close-up of an N-terminal loop overlay of the crystal structures of (c) the C318A (gray; PDB entry 2hgw) and C318A/C315CSD (blue) mutants and (d) the oxidized wild type (orange/yellow; PDB entry 2hhf) and the C318A/C315CSD mutant (blue). The N-terminal loop (residues 15–32, highlighted by the square) of the C318A mutant is interpreted in both monomers, whereas it is much more flexible and remains uninterpreted in both monomers of the C318A/C315CSD mutant (c) and one monomer of the oxidized wild type (d). |
![[Figure 2]](rf5027fig2.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
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