Figure 3
The EcFtsZ(L178E) filament. (a) Side-by-side comparison (after aligning the middle subunit) of the EcFtsZ(L178E) filament (red) generated by its crystal structure packing and the filament observed in the T-state SaFtsZ structure (PDB entry 3voa; yellow). The position of the T7 loop in each subunit is labeled, showing that this key catalytic loop is not properly positioned in the EcFtsZ filament (next to the GTP) as in the T-state filament. (b) Close-up view of the intersubunit contacts in the EcFtsZ(L178E) filament. |