Figure 4
Stereoview of ligand 4 in a representative AcAChBP binding site. In this case, the site is formed between subunit A (principal side) and subunit D (complementary side). A similar color scheme to Fig. 2(b) is used with the following additions: S-atom positions are shown in yellow, glycerol C atoms are shown in black and the side chain of a Met133 rotamer from a complex with cytisine (PDB entry 5syo) directed into the binding site is shown with blue C atoms. |