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Figure 1
Schematic domain structures of chicken FANCM, MHF1 and MHF2. FANCM has an SF2 helicase domain at the N-terminus followed by an MHF interaction domain and an ERCC4 nuclease-like domain at the C-­terminus. MHF binding indicates an interface with MHF. MHF is composed of MHF1 and MHF2, both of which contain a histone fold (HF). MHF1 contains an additional intrinsically disordered region. For crystallization and biochemical analysis, MHF1 was truncated at Glu106.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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