Figure 3
Primary-sequence alignment of acetoacetyl-CoA reductases from R. felis (PDB entry 4kms) and B. pseudomallei (PDB entry 3ezl) and of FabGs from S. aureus (PDB entry 3osu) and B. anthracis (PDB entry 2uvd). Secondary-structural elements shown include α-helices (α), 310-helices (η), β-strands (β) and β-turns (TT). Identical residues are shown in white on a red background, while conserved residues are shown in red and related residues are outlined in blue. Asterisks indicate conserved residues implicated in functional specificity. The image was generated using ESPript (Robert & Gouet, 2014). |