issue contents
February 2021 issue
research communications
In this study, biochemical and mass-spectrometric experiments, as well as features of the Phenix software package, were used to determine which residues to model into a segment of electron density of unknown origin.
PDB reference: CBL–SLAP2 complex, 6xar
Staphylococcus aureus SdrC forms a unique dimer through homophilic interactions, and a sandwich-like clamp at the C-terminus is formed by the two monomers in the stabilized SdrC dimer. Comparison with other Sdr proteins led to the proposal of a model for the confomational change of SdrC upon ligand binding.
PDB reference: N2 and N3 domains of SdrC, 6leb
The structure of acetoacetyl-CoA reductase from Rickettsia felis, the causative agent of flea-borne spotted fever, is reported. Acetoacetyl-CoA reductase is a key enzyme in both the glyoxylate/dicarboxylate and butanoate metabolic pathways.
PDB reference: acetoacetyl-CoA reductase from Rickettsia felis, 4kms