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Figure 3
Structural comparison of loop regions at the top of the Vap β-barrel. An all-against-all analysis was performed with the DALI server (Holm, 2020BB8) for truncated Vap structures, in which flexible (N- and C-termini) or variable (β2–β3 loop) residues had been removed. These six truncated Vap structures correspond to VapB residues 89–108 and 113–192. (a) Heat map of pairwise Z-scores. The bar on the right assigns colours to Z-­scores. The pairwise root-mean-square distances (r.m.s.d.s) are given in Supplementary Table S1. (b) VapD and the open VapB structure appear as outliers in correspondence analysis, a multidimensional scaling method that positions data points with the most similar structural neighbourhoods near each other. The horizontal and vertical axes represent the first and the second eigenvector, respectively.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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