Figure 5
Cavities in Vap structures. All Vaps were structurally aligned. The cartoon representation is coloured blue to red from the N-terminus to the C-terminus. The setting `Cavities and Pockets Only' in the surface representation of PyMOL was used to display completely enclosed and surface-accessible cavities as a transparent grey surface. Water molecules located completely or partially within these pockets are shown as red spheres. Only chain A of the new VapB structure (PDB entry 7b1z chain A) has a large, water-filled pocket between the β3–β4 loop and the β7–β8 loop. |