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Figure 3
Structural mapping of the pathological mutations found in the human TLDc domain from TBC1D24. The mutations are reported in the crystal structures of TLDcHs from NCOA7-AS (a) and TLDcDm from fly TBC1D24 (b). The human pathological missense mutations reported in TBC1D24 are indicated in black, while the corresponding residues are in blue for the TLDcHs structure and in red for the TLDcDm structure. Residues corresponding to the mutations are shown as yellow spheres.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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