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Figure 4
The active site of SmTetX is located at the re site. (a) Composition of the active site in combined stick and secondary-structure representation. C atoms of the substrate-binding domain are coloured red, those of the FAD-binding domain green and those of the C-terminal helix blue. The chloride anion is shown as a yellow sphere. (b, c) Alignment of SmTetX with the TetX–chlortetracycline (CTC) complex (Volkers et al., 2011 ![]() |