issue contents
October 2023 issue
research communications
Open access
Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin–antitoxin operon
Crystallization strategies for and structural analyses of all of the players in the faRel2/aTfaRel2 toxin–antitoxin system are reported.
The crystal structure of a soluble family I inorganic pyrophosphatase from L. pneumophila Philadelphia 1 was determined to a resolution of 2.0 Å. Inorganic pyrophosphatases play a central role in regulating cellular pyrophosphate concentration, which is important for many biosynthetic pathways. L. pneumophila Philadelphia 1 causes a rare but severe respiratory infection known as Legionnaires' disease.
methods communications
Open access
Guidance is provided on depositing raw diffraction data to support the results described in a macromolecular crystallography paper.
scientific commentaries
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The article by Moorefield et al. [(2023), Acta Cryst. F79, 257–266] demonstrates how structural genomics depositions can be used in undergraduate teaching.