Figure 4
Structural comparison of adenylation domains. The common motif is shown in red. The P-loop is shown in yellow. (a) The ATPPase domain (residues 189–390) of TtGuaA with the XMP and ATP model structure. The C atoms of XMP and ATP are shown in silver and orange, respectively. (b) The adenylation domain of firefly luciferase (residues 200–355 of PDB entry 1lci). (c) The adenylation domain of acyl-CoA synthetase from T. thermophilus (residues 200–360 of PDB entry 1ult). (d) Superposition of the three adenylation domains. |