Figure 16
(a) Ribbon diagram of the M. tubercolosis FGD1 monomer with bound F420 and a citrate (red) in ball-and-stick representation (PDB entry 3b4y). IS are insertion sequences in the core barrel that are proposed to cap the active site. (b) View of the active site; water molecules are shown as red spheres (reproduced from Bashiri et al., 2008). |