Figure 1
Quaternary structure of His-TvMIF. All three structures reveal prototypical MIF trimers. (a) The apo structure (PDB entry 8uz4) and (b) an attempt at co-crystallization with sodium 4-hydroxyphenylpyruvate (PDB entry 8ur4) are prototypical MIF trimers. (c) The co-crystal with pyruvate (PDB entry 8ur2) is a dimer of two prototypical MIF trimers. |