 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 2]](us5157fig2mag.jpg)
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Figure 2
(a) DMAPP binding into FARM in Rv2173. (b) IPP binding into FARM and SARM in Rv2173. (c) Overlay of the FARM and SARM allylic/DMAPP binding site in DMAPP-bound and IPP-bound structures. The DMAPP-bound structure is coloured light pink, with metal ions as green spheres and DMAPP as pink sticks. The IPP-bound structure is coloured blue, with metal ions as green spheres and the IPP and acetate as purple sticks. Waters are shown as red spheres and polar contacts as grey dashes. (d) Overlay of the IPP-bound (blue), DMAPP-bound (light pink) and apo (white) structures with a focus on the differences in the C-terminus leading to active-site closure. |
![[Figure 2]](us5157fig2.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
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