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Figure 1
Overall structure of P10VF-Lig bound to nicked DNA. (a) DNA ligase shown as a surface. (b) DNA ligase rendered as a cartoon to show secondary-structure elements. (c) Detailed view of the 5′ DNA–adenylate `step 2' intermediate captured in the crystal structure. (d) Detailed view of noncovalent interactions between the DB and OB domains which complete the encirclement of the DNA duplex by P10VF-Lig. In all figures the DNA-binding domain is coloured gold, the nucleotidyl transferase domain is coloured red and the oligonucleotide-binding domain is coloured teal. DNA is shown in grey and AMP in green.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 81| Part 6| June 2025| Pages 249-254
https://doi.org/10.1107/S2053230X2500411X
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