Crystal structure of the folded domains of Xrs2 from Saccharomyces cerevisiae

Vigneswaran, A.; Shi, K.; Aihara, H.; Evans, R.L.; Latham, M.P.

doi:10.1107/S2053230X25006867

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 3
Structural comparison of Sc Xrs2³²⁵ and Sp Nbs1³²⁹. (a) Overlay of the crystal structure of Sc Xrs2³²⁵ (colored as in Fig. 1

) with the crystal structure of Sp Nbs1³²⁹ (gray, PDB entry 3hue; Williams et al., 2009

). (b) Close-up view of the FHA region, highlighting differences in the loop region of Sp Nbs1 from The54 to Pro65 (depicted in orange) and Asp74 to Gln88 (magenta). (c) Isolated BRCT2 region, illustrating structural differences between the two proteins.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 81| Part 9| September 2025| Pages 365-373

https://doi.org/10.1107/S2053230X25006867

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