Diverse DTPA-chelated lanthanides with relevance for nuclear medicine bound to an engineered lipocalin reveal conserved ligand geometry

Mirwald, A.; Eichinger, A.; Skerra, A.

doi:10.1107/S2053230X26007624

Figure 1
Structures of the metal-chelate complexes and their binding to the Anticalin. (a) Formation of an octadentate M^III·DTPA-NH₂ complex and its chemical configuration. (b) Binding of the metal chelate to the ligand pocket of the Anticalin CL31d at the open end of the β-barrel.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 82| Part 9| September 2026| Pages 301-311

https://doi.org/10.1107/S2053230X26007624

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