Diverse DTPA-chelated lanthanides with relevance for nuclear medicine bound to an engineered lipocalin reveal conserved ligand geometry

Mirwald, A.; Eichinger, A.; Skerra, A.

doi:10.1107/S2053230X26007624

Figure 3
Affinities of the M^III·DTPA-NH₂ chelate complexes towards the Anticalin CL31d plotted against the respective ionic radius of the metal (CN = 6). Spheres correspond to lanthanide elements, while squares represent main-group metals; filled symbols denote those metal ions whose complexes with an Anticalin were elucidated by X-ray crystallography. The curve fit of the data points from fluorescence titration measurements is based on a spline function.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 82| Part 9| September 2026| Pages 301-311

https://doi.org/10.1107/S2053230X26007624

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