journal menuforthcoming articles
The following articles are a selection of those recently accepted for publication in Acta Crystallographica Section F: Structural Biology Communications.
See also Forthcoming articles in all IUCr journals.
research papersCrystal structure of Legionella pneumophila glycosidase effector LegY
We report the 1.46 Å resolution crystal structure of L. pneumophila GH15 glycosidase effector LegY, a single-domain protein with a canonical (α/α)6-barrel catalytic domain that is structurally and phylogenetically highly similar to fungal glucoamylases, and identify its conserved catalytic residues Glu206 and Glu405 that support a GH15-characteristic single-displacement catalytic mechanism; these findings provide pioneering structural and evolutionary insights into LegY, laying a foundation for understanding its role in L. pneumophila infection and the evolutionary dynamics of GH15 family enzymes.
methods communicationsWebCalEM: a browser-based tool for routine and accurate pixel-size calibration in cryo-EM
WebCalEM is a browser-based, install-free application that performs routine cryo-EM pixel-size calibration directly from gold or graphene oxide reflections in standard sample-support grids using subpixel Fourier-space peak localization; it reproduces the precision of established command-line calibration tools while removing the installation barrier and supporting retrospective per-region calibration on archived datasets.
