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The following articles are a selection of those recently accepted for publication in Acta Crystallographica Section F: Structural Biology Communications.
See also Forthcoming articles in all IUCr journals.
research communications (RC)Crystal structures of Escherichia coli glucokinase and insights into phosphate binding
This work presents the structure of apo Escherichia coli glucokinase (ecGLK) bound with sulfate, a phosphate mimic, and the structure of ecGLK in complex with both glucose and phosphate, implying a role for phosphate in regulating the glucokinase activity.
research communications (RC)research communications (RC)Structural insights into full-length human fascin1: a target for cancer treatment
This study presents the first fully resolved crystal structure of human fascin1, revealing its conformational plasticity and key interdomain interactions critical for actin bundling and cancer metastasis. These findings provide a structural foundation for the development of allosteric inhibitors and pave the way for time-resolved crystallographic studies to explore fascin1 dynamics in metastasis and drug targeting.
