Has AlphaFold3 achieved success for RNA?

This article presents a comprehensive evaluation of the performance of AlphaFold3 in predicting 3D structures of RNA, highlighting its limitations and comparing it with ten state-of-the-art methods. Our findings, based on benchmarks from five test sets, offer valuable insights into the challenges of RNA structure prediction.

TomoCPT: a generalizable model for 3D particle detection and localization in cryo-electron tomograms

TomoCPT is a generalizable transformer-based 3D particle-picking tool for cryo-tomographic data.

Reconsideration of the P-clusters in VFe proteins using the bond-valence method: towards their electron transfer and protonation

The oxidation of P^N clusters to P¹⁺/P²⁺ clusters corresponds to coordination by the hydroxyl group of serine and the amide group of cysteine without electron and proton transfers.

Stephen Harrop (1966–2024)

Stephen Harrop is remembered.