issue contents
May 2015 issue
Molecular parasitology - advances in biology and supporting drug discovery
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Cover illustration: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase in complex with DSM267 and FMN. Exploiting the hydrophobic `tunnel' to the FMN binding site enabled the structure-guided design of a potent and selective inhibitor of P. falciparum DHODH. For more details see the overview of the role of three-dimensional structures in the design of therapeutics targeting parasitic protozoa in this issue (Hol, p. 485).
molecular parasitology
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