Spotlight on structural biology
IUCr Journals and the International Year of Crystallography
The year 2014 has been declared by the United Nations as the International Year of Crystallography (IYCr2014) to celebrate 100 years of success following the first Nobel prize related to crystallography, awarded in 1914 to Max von Laue. The International Union of Crystallography (IUCr), working with UNESCO, is proud to be the custodian of the IYCr2014 and has embarked on a number of initiatives during the year. You can find out more about these activities by clicking here.
In celebration of IYCr2014 we are making a number of our papers from our biological journals free to download for a limited period of time.
For IYCr2014, the journals have published a number of special issues and collections of articles. For more information on special issues navigate through the special issues list in the sidebar on the right of this page.
The year also coincides with the launch of a fully open-access journal with the objective of attracting high-quality science papers of broad scientific significance from across all the scientific communities that use results obtained from diffraction methods. The journal is simply called IUCrJ and the six issues published this year are now available for everyone to read. The journal includes a biology and medicine section.
The IUCr publishes two journals focusing on structural biology.
Acta Crystallographica Section D: Biological Crystallography – Acta Cryst. D is a high-impact journal publishing articles covering any aspect of structural biology. This includes the structures of biological macromolecules and all the methods used to determine them.
Acta Crystallographica Section F: Structural Biology Communications – Acta Cryst. F is a rapid structural biology communications journal. Articles on any aspect of structural biology, including structures determined using high-throughput methods or from iterative studies such as those used in the pharmaceutical industry, are welcomed by the journal.
A selection of recent structural and molecular biology research articles in IUCr journals that are currently free to download are presented below.
BuD, a helix-loop-helix DNA-binding domain for genome modification
Stella, S., Molina, R., Lopez-Mendez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, G. (2014). Acta Cryst. D70, 2042-2052.
The structure of the C-terminal domain of the Zaire ebolavirus nucleoprotein
Dziubanska, P. J., Derewenda, U., Ellena, J. F., Engel, D. A. & Derewenda, Z. S. (2014). Acta Cryst. D70, 2420-2429.
In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27
Acosta-Reyes, F. J., Dardonville, C., de Koning, H. P., Natto, M., Subirana, J. A. & Campos, J. L. (2014). Acta Cryst. D70, 1614-1621.
Solving the RNA polymerase I structural puzzle
Moreno-Morcillo, M., Taylor, N. M. I., Gruene, T., Legrand, P., Rashid, U. J., Ruiz, F. M., Steuerwald, U., Muller, C. W. & Fernandez-Tornero, C. (2014). Acta Cryst. D70, 2570-2582.
Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA
Sidhu, N. S., Schreiber, K., Propper, K., Becker, S., Uson, I., Sheldrick, G. M., Gartner, J., Kratzner, R. & Steinfeld, R. (2014). Acta Cryst. D70, 1321-1335.
Structure of BamA, an essential factor in outer membrane protein biogenesis
Albrecht, R., Schutz, M., Oberhettinger, P., Faulstich, M., Bermejo, I., Rudel, T., Diederichs, K. & Zeth, K. (2014). Acta Cryst. D70, 1779-1789.
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA
Stella, S., Molina, R., Bertonatti, C., Juillerrat, A. & Montoya, G. (2014). Acta Cryst. F70, 87-91.
Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran
Tsirkone, V. G., Beutels, K. G., Demeulemeester, J., Debyser, Z., Christ, F. & Strelkov, S. V. (2014). Acta Cryst. F70, 723-729.
A drunken search in crystallization space
Fazio, V. J., Peat, T. S. & Newman, J. (2014). Acta Cryst. F70, 1303-1311.
Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolution
Schulz, E. C. & Barabas, O. (2014). Acta Cryst. F70, 1492-1497.
A new crystal form of a hyperthermophilic endocellulase
Kataoka, M. & Ishikawa, K. (2014). Acta Cryst. F70, 878-883.
Introduction to protein crystallization
McPherson, A. & Gavira, J. A. (2014). Acta Cryst. F70, 2-20.
Serial crystallography on in vivo grown microcrystals using synchrotron radiation
Gati, C., Bourenkov, G., Klinge, M., Rehders, D., Stellato, F., Oberthur, D., Yefanov, O., Sommer, B. P., Mogk, S., Duszenko, M., Betzel, C., Schneider, T. R., Chapman, H. N. & Redecke, L. (2014). IUCrJ, 1, 87-94.
The PDB_REDO server for macromolecular structure model optimization
Joosten, R. P., Long, F., Murshudov, G. N. & Perrakis, A. (2014). IUCrJ, 1, 213-220.
Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles
Aggarwal, M., Kondeti, B., Tu, C., Maupin, C. M., Silverman, D. N. & McKenna, R. (2014). IUCrJ, 1, 129-135.
Do we see what we should see? Describing non-covalent interactions in protein structures including precision
Gurusaran, M., Shankar, M., Nagarajan, R., Helliwell, J. R. & Sekar, K. (2014). IUCrJ, 1, 74-81.
Room-temperature serial crystallography using a kinetically optimized microfluidic device for protein crystallization and on-chip X-ray diffraction
Heymann, M., Opthalage, A., Wierman, J. L., Akella, S., Szebenyi, D. M. E., Gruner, S. M. & Fraden, S. (2014). IUCrJ, 1, 349-360.
Viruses and viral proteins
Verdaguer, N., Ferrero, D. & Murthy, M. R. (2014). IUCrJ, 1, 492-504.


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