Crystal structure and analytical profile of 1,2-di­phenyl-2-pyrrolidin-1-yl­ethanone hydro­chloride or `α-D2PV': a synthetic cathinone seized by law enforcement, along with its diluent sugar, myo-inositol

A confiscated package of street drugs was highly crystalline and was found to consist of two very different species accidentally of sizes convenient for X-ray diffraction, namely, 1,2-diphenyl-2-(pyrrolidin-1-yl)ethanone hydro­chloride or `α-D2PV' and the sugar myo-inositol.

A twofold interpenetrated two-dimensional zinc(II) coordination polymer for the highly sensitive detection of nitro­furan­toin in aqueous medium

A zinc(II) com­pound, prepared by reaction of Zn(NO₃)₂·6H₂O with 5-bromo­iso­phthalic acid and bis­[4-(2-methyl-1H-imidazol-1-yl)phen­yl]methanone in a mixture of water and di­methyl­acet­amide, possesses a new two-dimensional twofold inter­penetrated network, which can be simplified as a sql net. The com­pound displays a highly selective and sensitive detection for nitro­furan­toin (NFT) in aqueous solution. In addition, the possible fluorescence quenching mechanisms toward NFT are investigated.

Syntheses, crystal structures and inter­molecular inter­actions of six novel py­rimi­din-2-yl-substituted tri­aryl­tri­azoles

Six novel py­rimi­din-2-yl-based tri­aryl­tri­az­oles, namely, 4-(4-R-phen­yl)-3-(pyri­din-2-yl)-5-(py­rimi­din-2-yl)-1,2,4-tri­az­oles (with R = OCH₃, CH₃, H, Br, Cl and F) were synthesized and characterized by X-ray crystallography.

Crystal structure, inter­molecular inter­actions, charge–density distribution and ADME properties of the acridinium 4-nitro­benzoate and 2-amino-3-methyl­pyridinium 4-nitro­benzoate salts: a combined experimental and theoretical study

To enhance the properties of acridine and 2-amino-3-methyl­pyridine, 4-nitro­benzoic acid was chosen as a coformer, resulting in the formation of salts. Although both salts exhibit drug-like properties, the former salt has higher gastrointestinal absorption than the latter and hence it may be considered a potential drug candidate.

Three polymorphs of a new N,N′-di­propyl­ated isoindigo derivative

A dipropyl-substituted isoindigo derivative has three polymorphs with different mol­ecular conformations and arrangements.

Synthesis, crystal structure and in-silico evaluation of aryl­sul­fon­amide Schiff bases for potential activity against colon cancer

The successful synthesis, characterization and analysis of inter­molecular inter­actions of aryl­sul­fon­amide Schiff bases have been achieved, alongside their evaluation for inhibitory effects on tankyrase poly(ADP-ribose) polymerase in the context of colon cancer, through in-silico testing.