issue contents

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X

May 2024 issue

Highlighted illustration

Cover illustration: Tetrahedral nanocage cage component fused to anti-BARD1 DARPin [Agdanowski et al. (2024), Acta Cryst. F80, 107–115]. The structure of an imaging scaffold engineered to bind and study therapeutic protein targets has been determined. Cargo protein-binding DARPins are positioned within the large solvent channels of an unusually porous crystal lattice, suggesting that it may be possible to soak crystals with small target proteins in order to determine their structures.

research communications


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The high-resolution structure of the long Rib domain of the surface protein from Limosilactobacillus reuteri is reported. The data reveal a shared evolution of structural architecture with other modular domains of surface proteins.

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A crystallographic and biochemical study of the M405S variant of D. vulgaris formate dehydrogenase AB is reported in order to clarify the role of Met405 in catalysis in an enzyme that has applications in climate-change mitigation tools.

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The structure of an imaging scaffold engineered to bind and study therapeutic protein targets has been determined at 3.8 Å resolution. Cargo protein-binding DARPins are positioned within the large solvent channels of an unusually porous crystal lattice, suggesting that it may be possible to soak crystals with small target proteins in order to determine their structures.
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