Structure of Plasmodium vivax N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy

The 1.8 Å resolution ternary structure of P. vivax N-myristoyltransferase in complex with IMP-1088 and myristoyl-CoA is presented. IMP-1088 is an N-myristoyltransferase inhibitor from a family of inhibitors that are under investigation as antimalarials.

Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP

Recombinant N-terminally histidine-tagged H. pylori biotin protein ligase was purified and its 2.25 Å resolution co-crystal structure with biotinyl-5-ATP is reported.