Crystal structure and functional characterization of an Asp49 phospholipase A₂ from the bushmaster (Lachesis muta)

The crystal structure of an Asp49 phospholipase A₂ from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.

Crystal structures of Escherichia coli glucokinase acetylation-mimicking variants and insights into the impact of acetylation

This work reports the crystal structures of K214Q and K216Q variants of E. coli glucokinase, demonstrating a potential role of lysine acetylation in regulating glucokinase activity.

Crystal structure of a cold-active arginase from Glaciozyma antarctica

The crystal structure of the apo state of a cold-active arginase from the Antarctic yeast G. antarctica reveals that it retains the conserved arginase fold with regions of disorder.

A first structural model for covalent dimerization of S100 proteins

The first molecular description of a disulfide-crosslinked S100 homodimer is revealed by the crystallographic structure of an S100A6 variant bound to the receptor for advanced glycation end-products (RAGE). Sequence-conservation analyses and computational modeling suggest that this covalent architecture may be adopted by other S100 proteins, thus representing a conserved mode of covalent dimerization within the S100 family.

The atomic structure of human dystrophin spectrin-like repeat 24

The atomic structure of human dystrophin spectrin-like repeat 24 was determined at 2.14 Å resolution.