Crystal structure of betaine aldehyde de­hydrogenase from Burkholderia pseudomallei

High-resolution apo and cofactor-bound structures of betaine aldehyde dehydrogenase from Burkholderia pseudomallei are described.

Crystal structure of a short-chain de­hydrogenase/reductase from Burkholderia phymatum in complex with NAD

The crystal structure of a short-chain dehydrogenase/reductase from Burkholderia phymatum offers insights into its possible functions and likely inhibitors of its enzymatic functions.

Crystal structure of a hypothetical protein from Giardia lamblia

The 1.35 Å resolution crystal structure of a 15.6 kDa hypothetical protein from the parasite Giardia lamblia was determined as part of structural genomic studies to assign possible functions to hypothetical proteins from infectious agents. The structure has a prototypical endoribonuclease L-PSP (liver perchloric acid-soluble protein) topology with conserved allosteric active-site residues despite lacking any appreciable sequence identity to other members of this superfamily.

Structural and spectroscopic characterization of CO inhibition of [NiFe]-hydrogenase from Citrobacter sp. S-77

The 1.77 Å resolution crystal structure of the CO-bound state of [NiFe]-hydrogenase from Citrobacter sp. S-77 revealed that the exogenous CO ligand binds to the nickel ion in a bent conformation. The CO-bound state was identified as an EPR-silent Ni-SCO state by EPR and FT-IR spectroscopy.

Structural characterization of the urease accessory protein UreF from Klebsiella pneumoniae

The structure of the nickel-binding urease accessory protein UreF from Klebsiella pneumoniae is reported.

Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative

Structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with three novel ligands (JKPL38, JKP39 and JK122) were determined. In addition, the structure of a previously reported complex was updated to higher resolution by obtaining better quality crystals.

A crystal-processing machine using a deep-ultraviolet laser: application to long-wavelength native SAD experiments

A crystal-processing machine that uses a deep-ultraviolet laser has been developed. The machine can improve diffraction data by optimizing the crystal size and shape or by removing unnecessary portions of the crystal.